Etoposide versus Doxorubicin plus Olaratumab or Other Options

Most synovial sarcoma express NY-ESO-1 which is an antigen only found on cancer cells or on the testis which are anyway protected from the immune system. There are 2 main immunotherapy trials that target NY-ESO-1 expressing cells, using 2 different methods:
https://clinicaltrials.gov/ct2/show/NCT01343043
https://clinicaltrials.gov/ct2/show/NCT02387125
For more information about these trials, you can take a look here:

I don’t know if you noticed but at the top of the page, there is a drawing of a magnifying glass and if you click on it, you can do a search for NY-ESO-1 or anything else…