Hi everyone,
Today my oncologist offered me a place in a clinical trial called Axi-STS which uses a drug called Axitinib. I had bilateral thoracotomies with laser resection at the end of last year and my recent scan shows quite a lot of recurrence already.
I was wondering if anybody has had this drug and can tell me what side effects to expect?
Cheers
Is it the following trial?
https://clinicaltrials.gov/ct2/show/NCT01140737
Apparently, the trial is only held in UK so it may be difficult to find other patients with SS on the trial...
Wikipedia has a page with a list of adverse effects for this drug:
http://en.wikipedia.org/wiki/List_of_adverse_effects_of_axitinib
Here are the results of the phase III trial for pancreatic cancer in Japan:
http://jjco.oxfordjournals.org/content/early/2015/02/03/jjco.hyv011.long
It won't tell you if it works for sarcoma but it discusses adverse effects...
Yes, that’s it. I’ve been entered into the trial now. It is being used for 4 subtypes of STS including ours. It’s been described to me as the ‘second generation’ of pozapanib and they are hoping for it to either have a better or longer lasting effect. We will see.(I am being treated at a cancer centre by one of the leading sarcoma specialists in Europe, his name is Dr Mike Leahy)
Good luck! I hope it does work. We are in need of new treatment options!