Status of TH-302?

Symptoms and Treatments Chemo
1

Hi. Last I read, TH302 was showing promise in phase 3 clinical trials and big announcement of results were expected at end of 2014. Any idea what happened or if trials still underway?

Thanks

2

Good question and I am not sure what is the status. Take a look at this old article from MarketWatch:

http://www.marketwatch.com/story/threshold-pharmaceuticals-announces-its-phase-3-trial-of-th-302-in-patients-with-advanced-soft-tissue-sarcoma-will-continue-as-planned-following-protocol-specified-interim-analysis-2014-09-22

It sounds like they are still waiting for enough deaths to occur... Pretty shocking, isn't it?

3

The results came in and they are very disappointing :-(

http://www.targetedonc.com/news/maestro-trial-shows-evofosfamide-provides-little-benefit-in-sts